A Case of Conventional Kaposi' s Sarcoma / 대한피부과학회지

Convcntional Kaposi's sarcorna is distinguished frorn AIDS-associated Kaposi's sarcorna.. The authors report a case of 65 year-old male who presented with a nodular type of conventional Kaposi's sarcoma. The result of the serum antibody test against HTLV-3 in this patient was negative. Trial with b-interferon administered systemically and by local injection showed favorable results. Following 4 weeks of treatment, the tumor masses had markedly decreased in size. The authors suggest that b-interferon treatment for this patient was effectivc.

A Case of Epidermolytic Hyperkeratosis / 대한피부과학회지

Epidermolytic hyperkeratosis is a rare disease which is extremely variable in its severity. In some patients it may be so severe and generalized during the neonatal period as to be lifethreatening, in others, it is relatively inconspicuous. A bullous eruption is the characteristic finding of the epidermolytic hyperkeratosis The bullous episodes soon become less frequent and more localized and may eventually cesse, but continue into adult life after the age of 20 years in at least 20% of cases. A case of epidermolytic hyperkeratosis is represented. The patient was a 25-year-old male who had ichthyosiform erythroderma and the frequent episades of bullous eruption. The bullous eruption had been subsided under the treatment with oral penicillin administration. The histopathological features of the bullous lesion on his abdomen revealed the features of epidermolytic hyperkeratosis.

T and B Cells, T cell Subsets in Vitiligo Vulgaris / 대한피부과학회지

The basic pathophysiology of vitiligo is still obscure. Most researchers emphasized that poasible immunologic role is very important in pathophysiology of vitiligo. Also the type of vitiligo is classified by various type baaed on clinical manifestations. These facts promoted us to analyse the immunologic state in each type of vitiligo in order to verify whether there is present any immunologic alteration in this permatosis or any differences of immune state in each type of vitiligo. The following immune cells were analysed, T cell, B cell, and T cell subsets such as helper T cell and suppresaor T cell. Vitiligo vulgaris in our study showed alteration of immune cell such as low level of T cell and helper T cell.